Title: Building a Cell from Component Parts
Biology utilizes energy to organize itself from the nanoscale to the macroscopic scale. We are specifically interested in macromolecular complexes of the microtubule cytoskeleton can organize into different specific architectures using associated motor proteins and crosslinkers that are either active (use energy) or passive. We will present new data on a minimal microtubule, motor protein, and anti-parallel crosslinker system that can create cell-like structures similar to those found in mitosis. The system displays a phase diagram of extension and contraction depending on the relative microtubule and crosslinker densities. Similar results are observed in a model of self-propelled rods with preferentially anti-parallel interactions.
Every Friday 10:45-11:45 a.m., COB 267 (except as noted). Tea and cookies will be served from 10:30 - 10:45 a.m. Questions regarding the seminar series should be directed to Prof. Bin Liu